Why it is prescribed (Indications) : 
This medication is a benzodiazepine antagonist, prescribed for reversing drowsiness, sedation and other effects caused by benzodiazepine. It is also used for hepatic encephalopathy (confusion, altered level of consciousness and coma as a result of liver failure). 

When it is not to be taken (Contraindications): 
Contraindicated in patients with hypersensitivity, who have been given benzodiazepine for control of a potentially life-threatening condition, who have experienced with serious side effects due to overdose of depression medications.

Pregnancy Category : 
A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adult: IV- The recommended dose is 200 μg every 1�2 minutes until the effect is seen, to a maximum of 3 mg per hour.
How it should be taken : 
It comes as a solution for injection, to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of seizures, panic attacks, alcohol or drug dependency, breathing disorders, heart disease, liver disease, head injury, allergies, elderly, children, during pregnancy and breastfeeding. 
* Patient may develop with increased risk of epilepsy, respiratory depression, if it so consult with your doctor. 
* It may cause lightheadedness, dizziness or drowsiness, do not drive a car or operate machinery while taking this medication. 

Side Effects : 
Most frequent- Dizziness, injection site pain, increased sweating, headache and abnormal or blurred vision. 
Body as a Whole- Fatigue, weakness, uneasiness and injection site pain. 
Heart- Dilation of blood vessels, flushing, palpitations and hot flushes.
Gastrointestinal- Nausea, vomiting and dry mouth. 
Central Nervous System- Agitation, anxiety, nervousness, tremor, sleeplessness, and emotional lability. 
Respiratory- Difficulty in breathing. 
Other Precautions : 
* Avoid alcohol consumption.